Green tea may benefit people with bone-marrow disorders

                              Green tea may benefit people with bone-marrow disorders

The green tea that you drink to lose those extra pounds has many other powerful effects as a compound found in this ‘super-drink’ may have a life saving potential for people with bone-marrow disorders, reveals a study.

Green tea

                        Green tea

Green tea -Bone health

The health benefits of tea consumption in preventing cancers and cardiovascular diseases have been intensively investigated.Ingestion of green tea and green tea bioactive compounds may be beneficial in mitigating bone loss of this population and decreasing their risk of osteoporotic fractures.

Osteoporosis is a degenerative bone disease characterized by low bone mass and microarchitectural deterioration of bone tissue that leads to bone fragility and an increased susceptibility to fractures, especially in the hip, spine, and wrist.

Osteoporosis

              Osteoporosis

Geen tea -Researches:

The research appeared in the journal biological Researchers from Washington University in St. Louis in the U.S. and their German collaborators found that a compound epigallocatechine-3-gallate (EGCG), a polyphenol found in green tea leaves, may be of particular benefit to patients struggling with Osteoporosis, multiple myeloma and amyloidosis, often-fatal medical complications associated with bone-marrow disorders.

These patients are susceptible to a frequently fatal condition called light chain amyloidosis, in which parts of the body’s own antibodies become misshapen and can accumulate in various organs, including the heart and kidneys,” said study author Jan Bieschke from Washington University in St. Louis in the U.S.

The idea here is two fold: We wanted to understand how light chain amyloidosis works and how the green tea compound affects this specific protein,” Bieschke added

The team first isolated individual light chains from nine patients with bone marrow disorders that caused multiple myeloma or amyloidosis, then ran lab experiments to determine how the green tea compound affected the light chain protein.

The findings indicate that in bone marrow patients, the EGCG transformed light chain amyloid, preventing the misshapen form from replicating and accumulating dangerously.

“In the presence of green tea, the chains have a different internal structure, as the ECGC pulled the light chain into a different type of aggregate that wasn’t toxic and didn’t form fibril structures,” as happens to organs affected by amyloidosis,” ” Bieschke explained

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